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Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner.
J Exp Med. 2023 Jan 2;220(1):e20220829. doi: 10.1084/jem.20220829. Epub 2022 Nov 8.
J Exp Med. 2023.
PMID: 36346347
Free PMC article.
SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA.
Maharana S, Kretschmer S, Hunger S, Yan X, Kuster D, Traikov S, Zillinger T, Gentzel M, Elangovan S, Dasgupta P, Chappidi N, Lucas N, Maser KI, Maatz H, Rapp A, Marchand V, Chang YT, Motorin Y, Hubner N, Hartmann G, Hyman AA, Alberti S, Lee-Kirsch MA.
Maharana S, et al. Among authors: maser ki.
Mol Cell. 2022 Oct 6;82(19):3712-3728.e10. doi: 10.1016/j.molcel.2022.08.031. Epub 2022 Sep 22.
Mol Cell. 2022.
PMID: 36150385
Free article.
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